Search on: MISMATCH REPAIR ENDONUCLEASE PMS2 
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Descriptor English:   Mismatch Repair Endonuclease PMS2 
Descriptor Spanish:   Endonucleasa PMS2 de Reparación del Emparejamiento Incorrecto 
Descriptor Portuguese:   Endonuclease PMS2 de Reparo de Erro de Pareamento 
Synonyms English:   PMS-2 Protein
PMS1 Homolog 2, Mismatch Repair Protein
PMS2 Protein
Postmeiotic Segregation Increased-S. cerevisiae-2
PMS 2 Protein
Postmeiotic Segregation Increased S. cerevisiae 2  
Tree Number:   D08.811.074.766.250
D08.811.277.040.025.215.250
D08.811.277.352.335.350.600
D12.776.260.540.250
Definition English:   A MutL protein and component of the DNA MISMATCH REPAIR system. Its ENDONUCLEASE activity introduces SINGLE-STRAND DNA BREAKS which create entry points for EXO1 exonuclease to remove the strand containing the mismatch. It may also function in DNA DAMAGE signaling. 
History Note English:   2017 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   56466 
Unique Identifier:   D000070976 

Occurrence in VHL:
 

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